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Adv Sci (Weinh)：3D打印莲藕样仿生支架可有效诱导骨再生

2018-02-04 MedSci MedSci原创

关注

仿生材料近年来受到越来越多的关注。 大骨缺损的再生仍然是一个重大的临床挑战。 此外，血管形成在大骨再生过程中起重要作用，微通道结构可诱导内皮细胞形成血管。近年来，3D打印支架是大型骨缺损修复的主要材料。 然而，这些传统的三维支架具有低孔隙度和非通道结构，阻碍了血管生成和成骨。本研究从天然植物莲藕微观结构的角度出发，通过改进的3D打印策略，成功制备出具有莲藕状结构的仿生材料。结果显示，与传统的三维材

仿生材料近年来受到越来越多的关注。 大骨缺损的再生仍然是一个重大的临床挑战。 此外，血管形成在大骨再生过程中起重要作用，微通道结构可诱导内皮细胞形成血管。

近年来，3D打印支架是大型骨缺损修复的主要材料。 然而，这些传统的三维支架具有低孔隙度和非通道结构，阻碍了血管生成和成骨。

本研究从天然植物莲藕微观结构的角度出发，通过改进的3D打印策略，成功制备出具有莲藕状结构的仿生材料。结果显示，与传统的三维材料相比，这些仿生材料能明显提高体外细胞的附着和增殖，促进体内成骨，表明其可用于细胞传递和骨再生。

原始出处：

Chun Feng, Wenjie Zhang, 3D Printing of Lotus Root-Like Biomimetic Materials for Cell Delivery and Tissue Regeneration. Adv Sci (Weinh). 2017 Dec; 4(12): 1700401. doi:  10.1002/advs.201700401

评论区 (5)
#插入话题
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    2018-02-23 zjshifan_98647314

    #仿生支架#

    0

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    2018-02-06 ms9833124466084992

    #3D#

    0

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    2018-02-06 lsj630

    #骨再生#

    0

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    2018-02-04 changjiu

    学习一下谢谢

    0

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    2018-02-04 changjiu

    学习一下谢谢

    0