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Spago Nanomedical启动I期临床试验SPAGOPIX01

2018-12-22 MedSci MedSci原创

SPAGOPIX01SpagoNanomedical
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Spago Nanomedical制药公司近日向瑞典医疗和制药机构申请启动无钆造影剂SpagoPix（SN132D）在乳腺癌患者中的I期临床试验。

Spago Nanomedical制药公司近日向瑞典医疗和制药机构申请启动无钆造影剂SpagoPix（SN132D）在乳腺癌患者中的I期临床试验。该研究计划在瑞典乌普萨拉大学医院进行，目的是在监管部门批准后尽快开始招募患者。该临床试验的主要目的是记录无钆造影剂SpagoPix（SN132D）在乳腺癌患者中的安全性，另一个关键目标是研究SpagoPix（SN132D）对原发性和继发性肿瘤的磁共振成像（MRI）对比度的影响。

Spago Nanomedical 制药公司首席执行官Mats Hansen说：“SpagoPix项目正在按计划运行，我们向目标迈出了重要一步，为实体肿瘤MRI提供无钆造影剂”。MRI增强的机制与含碘造影剂在CT增强的机理不一样，磁共振造影剂是通过内外界弛豫效应和磁化率效应间接地改变组织的信号的强度，从而有效地提高了磁共振影像对比度，更易发现病变。


原始出处：

http://www.firstwordpharma.com/node/1613095#axzz5aJrWexZu

本文系梅斯医学（MedSci）原创编译整理，转载需授权！

评论区 (6)
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    2019-01-22 jeanqiuqiu

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    2018-12-26 医生2402

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    2019-06-08 gostraight

    #SpA#

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    2018-12-24 海豹

    #Medical#

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    2018-12-24 hb2008ye

    #Med#

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