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Semin Arthritis Rheu：湖北省IgG4-RD患者COVID-19 感染的临床特征

2020-05-20 xiangting MedSci原创

IgG4相关性疾病临床特征COVID‐19
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IgG4-RD患者属于COVID-19感染的易感人群，因此需要更细致的个人防护。

IgG4相关性疾病（IgG4-RD）是一种免疫介导的多器官、慢性进行性疾病。这项研究旨在调查湖北省IgG4-RD患者中COVID-19的易感性，并描述IgG4-RD患者COVID-19的临床表现。

一个随访系统纳入了过去10年间全国200多例IgG4-RD患者。共有91例生活在中国湖北的IgG4-RD患者对此项调查做出了回应。通过标准化的数据收集表格获得病史、临床症状、实验室检查、CT影像和治疗，然后由两名研究者独立进行审核。

91例患者中有2例感染了COVID-19。这两人均被归类为中等类型。诸如发烧、咳嗽的症状和影像学特征与其他COVID-19患者相似。这2例患者在连续口服小剂量糖皮质激素的情况下，均未出现IgG4-RD复发，也没有发展为严重或重症COVID-19。另外，2号患者SARS-CoV-2核酸转阴的时间很长。

IgG4-RD患者属于COVID-19感染的易感人群，因此需要更细致的个人防护。早期识别和适当治疗对于防止感染COVID-19的IgG4-RD患者发展为重症非常重要。

原始出处：

Yu Chen. Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China. Semin Arthritis Rheu. 16 May 2020.

评论区 (7)
#插入话题
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    2020-09-12 yeye5224612

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    #IgG#

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    2020-05-20 ms2000001409279728

    希望患者能撑过去

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