日本制药公司Sosei Heptares发现或可治疗COVID-19的小分子

2020-11-29 Allan MedSci原创

日本制药公司Sosei Heptares已在其COVID-19研发计划中确定了“最有前途”的小分子。

日本制药公司Sosei Heptares已在其COVID-19研发计划中确定了“最有前途”的小分子。Sosei早在4月就启动了该研发计划,旨在设计和开发针对SARS-CoV-2病毒的新型药物,该病毒可导致COVID-19。

该公司致力于利用SARS-CoV-2 Mpro蛋白酶的结构来设计针对SARS-CoV-2病毒和其他相关人类病毒的新型口服小分子药物。在该计划启动后,Sosei现在设计了三个具有抗病毒类药物特性的不同系列化合物,并开发了最具潜力的分子。

据Sosei称,这些有前途的化合物在抑制Mpro蛋白酶的活性方面已显示出很高的效力。Sosei Heptares负责人Miles Congreve说:“通过我们的SBDD平台识别有希望的小分子,并使其迅速通过设计阶段,以提供其作为COVID-19口服疗法的初步证据”。

 

原始出处:

http://www.pharmatimes.com/news/sosei_heptares_covid-19_programme_advances_promising_molecules_1357412

评论区 (9)
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    2021-04-16 cqlidoudou
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    2021-06-27 宋威
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17:10:00 CST 2020, time=2020-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903287, encodeId=399990328e6b, content=想学习想学习想学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/9iaAb4Jw2bbQql9icNGa5FjbmPicfSE7biaQIwz1AApCvib4HUmz3W6DibibX6BAgp4atWt9Qkox88aPJQY6GkvckxdfQ/132, createdBy=448e5312462, createdName=陈小凤, createdTime=Sun Nov 29 14:38:48 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903276, encodeId=7e479032e65e, content=打败新冠,共同进步。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201128/928bf083b196415cbaa5a8292d70e333/cdfe5f3f34794434be595ee70b8766e8.jpg, createdBy=69a95401355, createdName=ms9000001235733856, createdTime=Sun Nov 29 14:35:34 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903265, encodeId=05e390326555, content=希望有效, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201129/b5cbbe56f416461784f4cd3a1f07fac9/5dfb1f9c9f4c4d7f8d5f82b96a120488.jpg, createdBy=e4702774429, createdName=18327144a0m, createdTime=Sun Nov 29 14:12:18 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903233, encodeId=a8a4903233c1, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201126/cd191656b97f470781c0bd36448d9422/aa9a30b60c6646ad94bf6f39648feb47.jpg, createdBy=58b01524016, createdName=355366180, createdTime=Sun Nov 29 11:19:04 CST 2020, time=2020-11-29, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1794227, encodeId=435d1e94227f4, content=<a href='/topic/show?id=e6501655420' target=_blank style='color:#2F92EE;'>#Sosei#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16554, encryptionId=e6501655420, topicName=Sosei)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Fri Apr 16 12:15:17 CST 2021, time=2021-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1914709, encodeId=e7c31914e096a, content=<a href='/topic/show?id=84d7469559b' target=_blank style='color:#2F92EE;'>#小分子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46955, encryptionId=84d7469559b, topicName=小分子)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6105386, createdName=宋威, createdTime=Sun Jun 27 03:15:17 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1294588, encodeId=e212129458869, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Tue Dec 01 02:15:17 CST 2020, time=2020-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1591536, encodeId=c23e159153699, content=<a href='/topic/show?id=12cb3239087' target=_blank style='color:#2F92EE;'>#制药公司#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32390, encryptionId=12cb3239087, topicName=制药公司)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=36c517942572, createdName=xlwang2697, createdTime=Tue Dec 01 02:15:17 CST 2020, time=2020-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903591, encodeId=2e9c903591b5, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a> <a href='/topic/show?id=d61d32384ef' target=_blank style='color:#2F92EE;'>#制药#</a> 日本制药公司Sosei早在4月就启动了研发计划,旨在设计和开发针对SARS-CoV-2病毒的新型药物。, beContent=null, objectType=article, channel=null, level=null, likeNumber=234, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=32384, encryptionId=d61d32384ef, topicName=制药)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Mon Nov 30 17:10:00 CST 2020, time=2020-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903287, encodeId=399990328e6b, content=想学习想学习想学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/9iaAb4Jw2bbQql9icNGa5FjbmPicfSE7biaQIwz1AApCvib4HUmz3W6DibibX6BAgp4atWt9Qkox88aPJQY6GkvckxdfQ/132, createdBy=448e5312462, createdName=陈小凤, createdTime=Sun Nov 29 14:38:48 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903276, encodeId=7e479032e65e, content=打败新冠,共同进步。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201128/928bf083b196415cbaa5a8292d70e333/cdfe5f3f34794434be595ee70b8766e8.jpg, createdBy=69a95401355, createdName=ms9000001235733856, createdTime=Sun Nov 29 14:35:34 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903265, encodeId=05e390326555, content=希望有效, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201129/b5cbbe56f416461784f4cd3a1f07fac9/5dfb1f9c9f4c4d7f8d5f82b96a120488.jpg, createdBy=e4702774429, createdName=18327144a0m, createdTime=Sun Nov 29 14:12:18 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903233, encodeId=a8a4903233c1, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201126/cd191656b97f470781c0bd36448d9422/aa9a30b60c6646ad94bf6f39648feb47.jpg, createdBy=58b01524016, createdName=355366180, createdTime=Sun Nov 29 11:19:04 CST 2020, time=2020-11-29, status=1, ipAttribution=)]
    2020-11-30 BJying

    #新冠病毒# #制药# 日本制药公司Sosei早在4月就启动了研发计划,旨在设计和开发针对SARS-CoV-2病毒的新型药物。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1794227, encodeId=435d1e94227f4, content=<a href='/topic/show?id=e6501655420' target=_blank style='color:#2F92EE;'>#Sosei#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16554, encryptionId=e6501655420, topicName=Sosei)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Fri Apr 16 12:15:17 CST 2021, time=2021-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1914709, encodeId=e7c31914e096a, content=<a href='/topic/show?id=84d7469559b' target=_blank style='color:#2F92EE;'>#小分子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46955, encryptionId=84d7469559b, topicName=小分子)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6105386, createdName=宋威, createdTime=Sun Jun 27 03:15:17 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1294588, encodeId=e212129458869, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Tue Dec 01 02:15:17 CST 2020, time=2020-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1591536, encodeId=c23e159153699, content=<a href='/topic/show?id=12cb3239087' target=_blank style='color:#2F92EE;'>#制药公司#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32390, encryptionId=12cb3239087, topicName=制药公司)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=36c517942572, createdName=xlwang2697, createdTime=Tue Dec 01 02:15:17 CST 2020, time=2020-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903591, encodeId=2e9c903591b5, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a> <a href='/topic/show?id=d61d32384ef' target=_blank style='color:#2F92EE;'>#制药#</a> 日本制药公司Sosei早在4月就启动了研发计划,旨在设计和开发针对SARS-CoV-2病毒的新型药物。, beContent=null, objectType=article, channel=null, level=null, likeNumber=234, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=32384, encryptionId=d61d32384ef, topicName=制药)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Mon Nov 30 17:10:00 CST 2020, time=2020-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903287, encodeId=399990328e6b, content=想学习想学习想学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/9iaAb4Jw2bbQql9icNGa5FjbmPicfSE7biaQIwz1AApCvib4HUmz3W6DibibX6BAgp4atWt9Qkox88aPJQY6GkvckxdfQ/132, createdBy=448e5312462, createdName=陈小凤, createdTime=Sun Nov 29 14:38:48 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903276, encodeId=7e479032e65e, content=打败新冠,共同进步。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201128/928bf083b196415cbaa5a8292d70e333/cdfe5f3f34794434be595ee70b8766e8.jpg, createdBy=69a95401355, createdName=ms9000001235733856, createdTime=Sun Nov 29 14:35:34 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903265, encodeId=05e390326555, content=希望有效, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201129/b5cbbe56f416461784f4cd3a1f07fac9/5dfb1f9c9f4c4d7f8d5f82b96a120488.jpg, createdBy=e4702774429, createdName=18327144a0m, createdTime=Sun Nov 29 14:12:18 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903233, encodeId=a8a4903233c1, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201126/cd191656b97f470781c0bd36448d9422/aa9a30b60c6646ad94bf6f39648feb47.jpg, createdBy=58b01524016, createdName=355366180, createdTime=Sun Nov 29 11:19:04 CST 2020, time=2020-11-29, status=1, ipAttribution=)]
    2020-11-29 陈小凤

    想学习想学习想学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1794227, encodeId=435d1e94227f4, content=<a href='/topic/show?id=e6501655420' target=_blank style='color:#2F92EE;'>#Sosei#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16554, encryptionId=e6501655420, topicName=Sosei)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Fri Apr 16 12:15:17 CST 2021, time=2021-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1914709, encodeId=e7c31914e096a, content=<a href='/topic/show?id=84d7469559b' target=_blank style='color:#2F92EE;'>#小分子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46955, encryptionId=84d7469559b, topicName=小分子)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6105386, 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topicName=制药公司)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=36c517942572, createdName=xlwang2697, createdTime=Tue Dec 01 02:15:17 CST 2020, time=2020-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903591, encodeId=2e9c903591b5, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a> <a href='/topic/show?id=d61d32384ef' target=_blank style='color:#2F92EE;'>#制药#</a> 日本制药公司Sosei早在4月就启动了研发计划,旨在设计和开发针对SARS-CoV-2病毒的新型药物。, beContent=null, objectType=article, channel=null, level=null, likeNumber=234, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=32384, encryptionId=d61d32384ef, topicName=制药)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Mon Nov 30 17:10:00 CST 2020, time=2020-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903287, encodeId=399990328e6b, content=想学习想学习想学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/9iaAb4Jw2bbQql9icNGa5FjbmPicfSE7biaQIwz1AApCvib4HUmz3W6DibibX6BAgp4atWt9Qkox88aPJQY6GkvckxdfQ/132, createdBy=448e5312462, createdName=陈小凤, createdTime=Sun Nov 29 14:38:48 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903276, encodeId=7e479032e65e, content=打败新冠,共同进步。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201128/928bf083b196415cbaa5a8292d70e333/cdfe5f3f34794434be595ee70b8766e8.jpg, createdBy=69a95401355, createdName=ms9000001235733856, createdTime=Sun Nov 29 14:35:34 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903265, encodeId=05e390326555, content=希望有效, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201129/b5cbbe56f416461784f4cd3a1f07fac9/5dfb1f9c9f4c4d7f8d5f82b96a120488.jpg, createdBy=e4702774429, createdName=18327144a0m, createdTime=Sun Nov 29 14:12:18 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903233, encodeId=a8a4903233c1, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201126/cd191656b97f470781c0bd36448d9422/aa9a30b60c6646ad94bf6f39648feb47.jpg, createdBy=58b01524016, createdName=355366180, createdTime=Sun Nov 29 11:19:04 CST 2020, time=2020-11-29, status=1, ipAttribution=)]
    2020-11-29 ms9000001235733856

    打败新冠,共同进步。。

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1794227, encodeId=435d1e94227f4, content=<a href='/topic/show?id=e6501655420' target=_blank style='color:#2F92EE;'>#Sosei#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16554, encryptionId=e6501655420, topicName=Sosei)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Fri Apr 16 12:15:17 CST 2021, time=2021-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1914709, encodeId=e7c31914e096a, content=<a href='/topic/show?id=84d7469559b' target=_blank style='color:#2F92EE;'>#小分子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46955, encryptionId=84d7469559b, topicName=小分子)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6105386, createdName=宋威, createdTime=Sun Jun 27 03:15:17 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1294588, encodeId=e212129458869, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Tue Dec 01 02:15:17 CST 2020, time=2020-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1591536, encodeId=c23e159153699, content=<a href='/topic/show?id=12cb3239087' target=_blank style='color:#2F92EE;'>#制药公司#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32390, encryptionId=12cb3239087, topicName=制药公司)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=36c517942572, createdName=xlwang2697, createdTime=Tue Dec 01 02:15:17 CST 2020, time=2020-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903591, encodeId=2e9c903591b5, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a> <a href='/topic/show?id=d61d32384ef' target=_blank style='color:#2F92EE;'>#制药#</a> 日本制药公司Sosei早在4月就启动了研发计划,旨在设计和开发针对SARS-CoV-2病毒的新型药物。, beContent=null, objectType=article, channel=null, level=null, likeNumber=234, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=32384, encryptionId=d61d32384ef, topicName=制药)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Mon Nov 30 17:10:00 CST 2020, time=2020-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903287, encodeId=399990328e6b, content=想学习想学习想学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/9iaAb4Jw2bbQql9icNGa5FjbmPicfSE7biaQIwz1AApCvib4HUmz3W6DibibX6BAgp4atWt9Qkox88aPJQY6GkvckxdfQ/132, createdBy=448e5312462, createdName=陈小凤, createdTime=Sun Nov 29 14:38:48 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903276, encodeId=7e479032e65e, content=打败新冠,共同进步。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201128/928bf083b196415cbaa5a8292d70e333/cdfe5f3f34794434be595ee70b8766e8.jpg, createdBy=69a95401355, createdName=ms9000001235733856, createdTime=Sun Nov 29 14:35:34 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903265, encodeId=05e390326555, content=希望有效, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201129/b5cbbe56f416461784f4cd3a1f07fac9/5dfb1f9c9f4c4d7f8d5f82b96a120488.jpg, createdBy=e4702774429, createdName=18327144a0m, createdTime=Sun Nov 29 14:12:18 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903233, encodeId=a8a4903233c1, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201126/cd191656b97f470781c0bd36448d9422/aa9a30b60c6646ad94bf6f39648feb47.jpg, createdBy=58b01524016, createdName=355366180, createdTime=Sun Nov 29 11:19:04 CST 2020, time=2020-11-29, status=1, ipAttribution=)]
    2020-11-29 18327144a0m

    希望有效

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1794227, encodeId=435d1e94227f4, content=<a href='/topic/show?id=e6501655420' target=_blank style='color:#2F92EE;'>#Sosei#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16554, encryptionId=e6501655420, topicName=Sosei)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Fri Apr 16 12:15:17 CST 2021, time=2021-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1914709, encodeId=e7c31914e096a, content=<a href='/topic/show?id=84d7469559b' target=_blank style='color:#2F92EE;'>#小分子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46955, encryptionId=84d7469559b, topicName=小分子)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6105386, 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topicName=制药公司)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=36c517942572, createdName=xlwang2697, createdTime=Tue Dec 01 02:15:17 CST 2020, time=2020-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903591, encodeId=2e9c903591b5, content=<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a> <a href='/topic/show?id=d61d32384ef' target=_blank style='color:#2F92EE;'>#制药#</a> 日本制药公司Sosei早在4月就启动了研发计划,旨在设计和开发针对SARS-CoV-2病毒的新型药物。, beContent=null, objectType=article, channel=null, level=null, likeNumber=234, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=32384, encryptionId=d61d32384ef, topicName=制药)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Mon Nov 30 17:10:00 CST 2020, time=2020-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903287, encodeId=399990328e6b, content=想学习想学习想学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/9iaAb4Jw2bbQql9icNGa5FjbmPicfSE7biaQIwz1AApCvib4HUmz3W6DibibX6BAgp4atWt9Qkox88aPJQY6GkvckxdfQ/132, createdBy=448e5312462, createdName=陈小凤, createdTime=Sun Nov 29 14:38:48 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903276, encodeId=7e479032e65e, content=打败新冠,共同进步。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201128/928bf083b196415cbaa5a8292d70e333/cdfe5f3f34794434be595ee70b8766e8.jpg, createdBy=69a95401355, createdName=ms9000001235733856, createdTime=Sun Nov 29 14:35:34 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903265, encodeId=05e390326555, content=希望有效, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201129/b5cbbe56f416461784f4cd3a1f07fac9/5dfb1f9c9f4c4d7f8d5f82b96a120488.jpg, createdBy=e4702774429, createdName=18327144a0m, createdTime=Sun Nov 29 14:12:18 CST 2020, time=2020-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903233, encodeId=a8a4903233c1, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201126/cd191656b97f470781c0bd36448d9422/aa9a30b60c6646ad94bf6f39648feb47.jpg, createdBy=58b01524016, createdName=355366180, createdTime=Sun Nov 29 11:19:04 CST 2020, time=2020-11-29, status=1, ipAttribution=)]
    2020-11-29 355366180

    不错

    0

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