JAMA Intern Med:心身疗法、疼痛与阿片药物

2019-11-05 MedSci MedSci原创

研究结果表明,心身疗法与疼痛改善和阿片类药物剂量减少有关

心身疗法(MBTs)正在成为解决阿片类药物危机的潜在工具。近日研究人员评价MBTs与疼痛人群阿片类药物剂量减少的相关性。

本次研究为系统回顾和荟萃分析,收集截至2018年3月相关研究数据,主要结局为疼痛强度。次要结局为阿片类药物剂量、阿片类误用、阿片类成瘾、残疾或功能。

60篇论文,6404名参与者被纳入了荟萃分析。总的来说,MBTs与疼痛减轻(Cohen d=-0.51;)和阿片类药物剂量减少(Cohen d=-0.26)有关。在涉及冥想(n=5)、催眠(n=25)、放松(n=14)、引导图像(n=7)、治疗建议(n=6)和认知行为疗法(n=7)的干预措施中,冥想(-0.70)、催眠(-0.5 4)、暗示(-0.6 8)和认知行为治疗(-0.4 3)对疼痛结局有中到大的改善,但其他方案的效果不显著。尽管大多数冥想(n=4[80%])、认知行为疗法(n=4[57%])和催眠(n=12[63%])的研究发现阿片相关的结果有所改善,但涉及暗示、引导和放松的研究较少。

研究结果表明,心身疗法与疼痛改善和阿片类药物剂量减少有关。

原始出处:

Eric L. Garland et al. Mind-Body Therapies for Opioid-Treated Pain A Systematic Review and Meta-analysis. JAMA Intern Med. November 4, 2019.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

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