J Affect Disord:血浆低维生素D浓度与老年抑郁症状相关

2015-10-27 phylis 译 MedSci原创

背景:这篇研究旨在确定血浆25羟维生素D的浓度和韩国老年任抑郁症的相关性。方法:这篇研究应用来自于韩国城市农村老年人研究中的数据,共招募2942名年龄在65岁以上的城市和农村人口。排除抗抑郁药治疗的患者,研究者对2853名受试者(962名为男性,1891名女性)进行分析。血浆25羟维生素D作为连续分类变量进行分析。应用韩国老年抑郁简明量表进行抑郁症状的评估。应用多变量logistic回归分析男性和

背景:这篇研究旨在确定血浆25羟维生素D的浓度和韩国老年任抑郁症的相关性。

方法:这篇研究应用来自于韩国城市农村老年人研究中的数据,共招募2942名年龄在65岁以上的城市和农村人口。排除抗抑郁药治疗的患者,研究者对2853名受试者(962名为男性,1891名女性)进行分析。血浆25羟维生素D作为连续分类变量进行分析。应用韩国老年抑郁简明量表进行抑郁症状的评估。应用多变量logistic回归分析男性和女性患者25羟维生素D和抑郁症状的相关性。

结果:男性受试者,校正研究时间、评估时间、年龄、甲状旁腺激素、BMI、共存病的数目、抽烟、饮酒、运动、睡眠时间、收入、教育、同居状态和居住区后,与血浆25羟维生素D浓度≥30.0ng/mL的受试者相比,血浆25羟维生素D的浓度为20.0-29.9, 10.0-19.9,及<10.0ng/mL的受试者,抑郁症状的OR(95%CI)分别为1.74 (0.85, 3.58)、 2.50 (1.20, 5.18)及2.81 (1.15, 6.83)。女性受试者,在校正前后,25羟维生素D浓度和抑郁症显著相关。

局限性:这是横断面的研究设计,因果关系不确定。未检测受试者维生素D的应用及户外活动量。

结论:研究表明血液中低浓度的维生素D的含量与老年人抑郁症状独立相关。

原文出处:

Song BM, Kim HC, Rhee Y, et al. Association between serum 25-hydroxyvitamin D concentrations and depressive symptoms in an older Korean population: A cross-sectional study. J Affect Disord. 2015,Oct 9.


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beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Oct 27 18:24:00 CST 2015, time=2015-10-27, status=1, ipAttribution=)]
    2016-05-10 cmsvly
  5. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Oct 27 18:24:00 CST 2015, time=2015-10-27, status=1, ipAttribution=)]
    2016-01-13 Lynee劲飞扬

    给力

    0

  6. 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  7. 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  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54980, encryptionId=952a54980e5, topicName=抑郁症状)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Oct 29 06:59:00 CST 2015, time=2015-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1544402, encodeId=3e5d154440247, content=<a href='/topic/show?id=ac3d6549e75' target=_blank style='color:#2F92EE;'>#浓度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65497, encryptionId=ac3d6549e75, topicName=浓度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=16b213663040, createdName=12498974m55暂无昵称, createdTime=Thu Oct 29 06:59:00 CST 2015, time=2015-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41683, encodeId=f7a34168304, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8b911658392, createdName=梦想天空, createdTime=Wed Oct 28 09:01:00 CST 2015, time=2015-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41558, encodeId=d44f415583a, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Oct 27 18:25:00 CST 2015, time=2015-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41555, encodeId=649b41555aa, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Oct 27 18:24:00 CST 2015, time=2015-10-27, status=1, ipAttribution=)]
    2015-10-28 梦想天空

    0

  9. 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replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54980, encryptionId=952a54980e5, topicName=抑郁症状)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Oct 29 06:59:00 CST 2015, time=2015-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1544402, encodeId=3e5d154440247, content=<a href='/topic/show?id=ac3d6549e75' target=_blank style='color:#2F92EE;'>#浓度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65497, encryptionId=ac3d6549e75, topicName=浓度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=16b213663040, createdName=12498974m55暂无昵称, createdTime=Thu Oct 29 06:59:00 CST 2015, time=2015-10-29, status=1, ipAttribution=), 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beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Oct 27 18:24:00 CST 2015, time=2015-10-27, status=1, ipAttribution=)]
    2015-10-27 sunlong28

    感谢分享

    0

  10. 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    2015-10-27 sunlong28

    0

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