Clinica Chimica Acta:患有代谢综合征的绝经后妇女的循环PCSK9浓度出现增加?

2019-09-13 gladiator MedSci原创

研究表明,高PCSK9浓度与心血管疾病(CVD)风险增加有关。本研究调查了泰国受试者人群的PCSK9浓度及其与代谢参数的关系,并比较了绝经前和绝经后伴有和不伴有代谢综合征(MetS)的妇女的PCSK9浓度。

研究表明,高PCSK9浓度与心血管疾病(CVD)风险增加有关。本研究调查了泰国受试者人群的PCSK9浓度及其与代谢参数的关系,并比较了绝经前和绝经后伴有和不伴有代谢综合征(MetS)的妇女的PCSK9浓度。

研究人员在436名泰国受试者(152名男性,143名绝经前和141名绝经后女性)中测量了人体测量数据、血脂、空腹血糖(FBG)PCSK9浓度。

研究发现,PCSK9浓度在女性中显着高于男性(p = .002),并且在MetS组分数量增加的受试者中增加(p =趋势= .011)。绝经后女性的PCSK9浓度显着高于绝经前女性(p <.001),MetS组比非MetS组(p = .037)和绝经后MetS女性高于没有MetS的绝经前女性( p <0.001)。血清PCSK9浓度与几个代谢参数正相关,包括年龄,BMI,收缩压(SBP),总胆固醇,甘油三酯,LDL-CFBG

研究表明,PCSK9浓度受泰国受试者的年龄,性别,MetS状态和绝经状态的影响。这些研究结果表明,PCSK9浓度升高可能会增加绝经后MetS患者的心血管风险。原始出处:

Nutjaree Jeenduang, Circulating PCSK9 concentrations are increased in postmenopausal women with the metabolic syndrome

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

 

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    2020-04-26 Tamikia
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    2020-01-11 FukaiBao
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    2020-01-07 windight
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  8. 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createdBy=979839152460, createdName=FukaiBao, createdTime=Sat Jan 11 18:04:00 CST 2020, time=2020-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849708, encodeId=5efc1849e08d8, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Tue Jan 07 11:04:00 CST 2020, time=2020-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1257221, encodeId=d7f0125e221cb, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sun Sep 15 13:04:00 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1332017, encodeId=d726133201e92, content=<a href='/topic/show?id=0ab6e8887cc' target=_blank style='color:#2F92EE;'>#绝经后妇女#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78887, encryptionId=0ab6e8887cc, topicName=绝经后妇女)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Sep 15 13:04:00 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431622, encodeId=2d9514316225e, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Sep 15 13:04:00 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1544594, encodeId=1a6b154459412, content=<a href='/topic/show?id=ac3d6549e75' target=_blank style='color:#2F92EE;'>#浓度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65497, encryptionId=ac3d6549e75, topicName=浓度)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sun Sep 15 13:04:00 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631618, encodeId=2199163161827, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sun Sep 15 13:04:00 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372693, encodeId=962f3e269359, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d551998554, createdName=1e1c07bdm01(暂无匿称), createdTime=Sat Sep 14 05:46:27 CST 2019, time=2019-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372689, encodeId=16e53e268978, content=学习了,很有用,不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Sep 14 00:24:41 CST 2019, time=2019-09-14, status=1, ipAttribution=)]
    2019-09-15 zxxiang
  9. 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objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Sep 14 00:24:41 CST 2019, time=2019-09-14, status=1, ipAttribution=)]
  10. 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href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sun Sep 15 13:04:00 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372693, encodeId=962f3e269359, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d551998554, createdName=1e1c07bdm01(暂无匿称), createdTime=Sat Sep 14 05:46:27 CST 2019, time=2019-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372689, encodeId=16e53e268978, content=学习了,很有用,不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Sep 14 00:24:41 CST 2019, time=2019-09-14, status=1, ipAttribution=)]
    2019-09-14 飛歌

    学习了,很有用,不错

    0