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J Clin Diagn Res：肾衰和牙周健康之间是否存在关联？

2017-12-31 MedSci MedSci原创

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本研究旨在评估接受血液透析的ESRD患者的牙周健康状况，并建立肾衰竭和牙周病之间的关系。在匹配年龄和性别后，研究纳入了80名对照和测试对象。测量每名患者的肌酐和GFR。记录口腔卫生指数-简化（OHI-S）、牙龈指数（GI）、牙周袋深度（PD）和临床附着水平（CAL）作为牙周参数以评估两组受试者之间的相关性。此外，试验组根据血液透析持续时间进行再分组，不到6个月，6个月至1年和1年以上。使用t检验和

本研究旨在评估接受血液透析的ESRD患者的牙周健康状况，并建立肾衰竭和牙周病之间的关系。

在匹配年龄和性别后，研究纳入了80名对照和测试对象。测量每名患者的肌酐和GFR。记录口腔卫生指数-简化（OHI-S）、牙龈指数（GI）、牙周袋深度（PD）和临床附着水平（CAL）作为牙周参数以评估两组受试者之间的相关性。此外，试验组根据血液透析持续时间进行再分组，不到6个月，6个月至1年和1年以上。使用t检验和方差分析进行组间和组内比较。

结果显示，测试组和对照组之间的所有牙周参数均存在明显的统计学差异。然而，亚组之间并没有发现存在统计学上的差异。

综上所述，研究发现接受血液透析的ESRD患者其牙周疾病严重程度受到患者身体虚弱状态的严重影响。透析时间在病情恶化方面发挥微弱的作用。仍需进一步的研究来加强建立肾脏疾病和牙周状况之间的双向关系。

原始出处：

Chhokra M, Manocha S, et al., Establishing an Association between Renal Failure and Periodontal Health: A Cross Sectional Study. J Clin Diagn Res. 2013 Oct;7(10):2348-50. doi: 10.7860/JCDR/2013/5937.3521. Epub 2013 Oct 5.

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    2018-05-10 ms9608593228839890

    #DIA#

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