J Burn Care Res:严重烧伤和烟吸入的烧伤患者低肺功能与骨骼肌指数的关系

2020-02-19 不详 网络

本报告旨在评估重度烧伤和烟雾吸入患者的肺功能,呼吸肌力量和骨骼肌指数(SMI)之间的关系。研究共分析了54名吸入烧伤患者。阑尾骨骼肌质量(ASM)是手臂和腿部肌肉质量的总和。 SMI正在使用体重指数(ASM / BMI)来调整体重。进行肺活量测定以评估肺功能。肺功能测试包括峰值咳嗽流量(PCF),强制肺活量(FVC),1秒强制呼气量(FEV1),介于FVC(FEF 25-75)的25%至75%之间

本报告旨在评估重度烧伤和烟雾吸入患者的肺功能,呼吸肌力量和骨骼肌指数(SMI)之间的关系。

研究共分析了54名吸入烧伤患者。阑尾骨骼肌质量(ASM)是手臂和腿部肌肉质量的总和。 SMI正在使用体重指数(ASM / BMI)来调整体重。进行肺活量测定以评估肺功能。肺功能测试包括峰值咳嗽流量(PCF),强制肺活量(FVC),1秒强制呼气量(FEV1),介于FVC(FEF 25-75)的25%至75%之间的强制呼气流量,FEV1 / FVC比率表示为百分比(FEV1 / FVC%),呼气峰值流量(PEF)和最大自主通气量(MVV)。测量呼气和吸气的肌肉强度。研究了肺功能,呼吸肌力量和SMI之间的关系。

结果显示,SMI与PCF(r = 0.34和p = 0.02),FVC(r = 0.55和p <0.001),FEV1(r = 0.45和p = 0.001),PEF(r = 0.35和p = 0.01)显着相关。在包括年龄,TBSA,机械通气时间和烧伤后天数在内的多元回归分析中,SMI与FVC,PCF,FEV1,FEV1 / FVC和PEF显着相关(p <0.001,p = 0.02,p = 0.001,p = 0.04和p = 0.03)。严重烧伤和烟雾吸入患者的肺功能测试与SMI明显相关。

综上所述,该研究结果表明,烧伤患者的肌肉消瘦强化治疗对改善肺功能很重要。

原始出处:

Won YH1, Cho YS2, et al., Relation Between Low Pulmonary Function and Skeletal Muscle Index in Burn Patients with Major Burn Injury and Smoke Inhalation: A Retrospective Study. J Burn Care Res. 2020 Jan 30. pii: iraa015. doi: 10.1093/jbcr/iraa015.

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