A型血友病治疗前沿:SubQ-8(一种新型重组FVIII)的新近进展

2019-07-08 Allan MedSci原创

Octapharma公司近日在第27届国际血栓形成和止血学会(ISTH)的科学研讨会上介绍了SubQ-8临床开发计划和临床前数据的最新情况。SubQ-8将人细胞系衍生的重组FVIII(simoctocog alfa)与人细胞系中产生的重组VWF片段二聚体相结合,以促进皮下摄入FVIII。

Octapharma公司近日在第27届国际血栓形成和止血学会(ISTH)的科学研讨会上介绍了SubQ-8临床开发计划和临床前数据的最新情况。SubQ-8将人细胞系衍生的重组FVIIIsimoctocog alfa)与人细胞系中产生的重组VWF片段二聚体相结合,以促进皮下摄入FVIIIOctapharma董事会成员Olaf Walter说:“Octapharma致力于改善凝血功能障碍患者的生活质量,我们很自豪能够开发出具有这种潜力的产品,以满足A型血友病患者的主要需求

A型血友病是由于缺乏第8凝血因子(即FVIII)所引起的,是临床上最常见的血友病,约占血友病人数的80%-85%,在某些血友病高发地区甚至更高。 


原始出处:

http://www.firstwordpharma.com/node/1651657#axzz5syvQI0kQ

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

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