Clin Implant Dent Relat Res:喷砂氧化锆植体的酸性和碱性蚀刻对骨整合的影响

2019-01-05 MedSci MedSci原创

氧化锆(ZrO2)作为牙科材料受到关注;然而,关于表面改性对氧化锆植体骨整合的影响知之甚少。本研究旨在确定喷砂ZrO2植体的酸性或碱性蚀刻对植体体内骨整合的影响。将具有两个环形凹槽的圆柱形ZrO2植体植入12只小型猪的上颌骨中。在愈合后1,2,4和8周进行活组织检查。未脱钙部分进行甲苯胺蓝染色。通过组织形态学确定骨与植体的接触,骨区域和多核巨细胞的存在。进行了未经校正的探索性统计分析。结果显示,喷

氧化锆(ZrO2)作为牙科材料受到关注;然而,关于表面改性对氧化锆植体骨整合的影响知之甚少。本研究旨在确定喷砂ZrO2植体的酸性或碱性蚀刻对植体体内骨整合的影响。

将具有两个环形凹槽的圆柱形ZrO2植体植入12只小型猪的上颌骨中。在愈合后1,2,4和8周进行活组织检查。未脱钙部分进行甲苯胺蓝染色。通过组织形态学确定骨与植体的接触,骨区域和多核巨细胞的存在。进行了未经校正的探索性统计分析。

结果显示,喷砂ZrO2植体的酸蚀刻而非碱性蚀刻比喷砂ZrO2植体产生更多的骨-种植体接触。骨区域不受表面改性的影响。酸性和碱性蚀刻都增加了植体表面多核巨细胞的形成。本研究为进一步研究喷砂ZrO2种植体酸蚀对骨整合的影响以及多核巨细胞在此过程中的作用提供了科学依据。

原始出处:

Saulacic N, Erdosi R, Bosshardt DD, Gruber R, Buser D. Acid and alkaline etching of sandblasted zirconiaimplants: a histomorphometric study in miniature pigs. Clin Implant Dent Relat Res 2014: 16: 313-322.

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    2019-04-28 xuyong536
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    2019-06-02 xuyu
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