J Oral Implantol:羊膜移植与可吸收胶原膜诱导骨形成的效果对比

2018-04-11 MedSci MedSci原创

本研究旨在评估羊膜保护移植物与胶原膜保护移植物修复犬胫骨骨缺损的效果。研究选取了4只>1.5岁的伊朗混血狗,使用其胫骨进行探究。去除骨膜后,使用16 mm环钻制备类似的孔(共38个孔)。实验组,10个孔使用可吸收胶原蛋白覆盖,16个孔使用羊膜覆盖。对照组中制备12个孔,并覆盖上面的软组织。6周和12周后暴露胫骨,收集样本并进行组织学处理。通过组织形态计量学研究评估新骨形成。本研究包括四只年龄超过1

本研究旨在评估羊膜保护移植物与胶原膜保护移植物修复犬胫骨骨缺损的效果。

研究选取了4只>1.5岁的伊朗混血狗,使用其胫骨进行探究。去除骨膜后,使用16 mm环钻制备类似的孔(共38个孔)。实验组,10个孔使用可吸收胶原蛋白覆盖,16个孔使用羊膜覆盖。对照组中制备12个孔,并覆盖上面的软组织。6周和12周后暴露胫骨,收集样本并进行组织学处理。通过组织形态计量学研究评估新骨形成。本研究包括四只年龄超过1.5岁的。

结果显示,与胶原组相比,对照组新骨形成较少(p = 0.863)。胶原蛋白组的骨形成少于羊膜组(p = 0.194),但这种差异并不明显。然而,羊膜组的骨形成明显多于对照组(p = 0.050)。

综上所述,该研究结果表明,使用羊膜似乎加速了引导骨再生中的骨形成。然而,仍需进一步的研究以探究其对骨愈合的临床影响。

原始出处:

Koushaei S, Samandari MH, et al., Histological Comparison of New Bone Formation Using Amnion Membrane Graft vs Resorbable Collagen Membrane: An Animal Study. J Oral Implantol. 2018 Apr 2. doi: 10.1563/aaid-joi-D-16-00120. 

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    2018-07-10 xuyu
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    2018-11-23 xuyong536
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    2018-12-04 小几洁