World Neurosurg:Moyamoya病患者皮层微血管的结构形态或许是一种代偿机制

2017-07-11 shaosai MedSci原创

在moyamoya病中,微血管直径的扩张是较为常见的,并被称为微血管化。本研究的目的是通过影像学技术来分析moyamoya病皮质微血管形成的店,并探究皮层表面侧支循环的形成机制。

在moyamoya病中,微血管直径的扩张是较为常见的,并被称为微血管化。本研究的目的是通过影像学技术来分析moyamoya病皮质微血管形成的店,并探究皮层表面侧支循环的形成机制。

本研究共纳入了14例moyamoya病患者的20侧病变半球。从术中对脑皮层表面的侧支血管图像进行采集,随后创建二值图像。然后,计算脑表面微血管形成的比例(血管分数; VF)和分形维数(Db)值。然后将moyamoya病的VF和Db值与动脉粥样硬化疾病和非缺血性疾病相比较,并对临床和放射因素进行评估。

在moyamoya病中,VF值明显高于动脉粥样硬化疾病,Db值明显高于动脉粥样硬化性疾病和非缺血性疾病。在moyamoya病中,VF值与磁共振血管造影(MRA)评分呈中度相关。此外, Db与儿科患者、缺血性症状的存在和常春藤征的存在中度相关性,Db值同时也与显示与moyamoya病的MRA评分和CBF呈中度相关。

研究结果表明:moyamoya病的皮层微血管形成表现为分形维数增加以及软膜血管的扩张。在moyamoya病中,皮质微血管形成与临床和放射学因素有关。这种微血管形成可能是moyamoya疾病缺血状态下的代偿机制。

原始出处:

Komatsu K, Mikami T, Suzuki H, Geometrical complexity of cortical microvascularization in moyamoya disease. World Neurosurg.. 2017. DOI: 10.1016/J.WNEU.2017.06.124

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1700277, encodeId=cf681e0027768, content=<a href='/topic/show?id=50331215910' target=_blank style='color:#2F92EE;'>#Moyamoya病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12159, encryptionId=50331215910, topicName=Moyamoya病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f96f30025701, createdName=jj000011, createdTime=Mon Nov 20 00:14:00 CST 2017, time=2017-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=223078, encodeId=18992230e814, content=M0Yam0ya病患者的治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Mon Jul 17 07:26:34 CST 2017, time=2017-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=221874, encodeId=80262218e4ae, content=不需要多大样本量, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Thu Jul 13 13:28:29 CST 2017, time=2017-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364204, encodeId=367b13642040c, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Thu Jul 13 07:14:00 CST 2017, time=2017-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365320, encodeId=1bd013653204f, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Thu Jul 13 07:14:00 CST 2017, time=2017-07-13, status=1, ipAttribution=)]
    2017-07-17 jyzxjiangqin

    M0Yam0ya病患者的治疗。

    0

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    2017-07-13 baihao215

    不需要多大样本量

    0

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    2017-07-13 lsndxfj
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    2017-07-13 mgqwxj