BMC Geriatr:晚期残牙数量与痴呆发生率之间的关系

2018-02-28 MedSci MedSci原创

晚年的牙齿丧失可能会增加痴呆症的发病率。本分析的目的是系统地回顾目前关于剩余牙齿数与晚年痴呆发生率之间关系的证据。对2017年3月25日以前发表的文章的相关参数进行了科学文献的多个数据库检索。发现了报告晚年痴呆和残牙发病率的多队列研究,观察期为2.4至32年。评估随机效应合并优势比(OR)和95%置信区间(CI),以检查后期高残留牙齿数是否与痴呆风险降低相关。异质性由I 2测量。建议评估,开发和评

晚年的牙齿丧失可能会增加痴呆症的发病率。本分析的目的是系统地回顾目前关于剩余牙齿数与晚年痴呆发生率之间关系的证据。

对2017年3月25日以前发表的文章的相关参数进行了科学文献的多个数据库检索。发现了报告晚年痴呆和残牙发病率的多队列研究,观察期为2.4至32年。评估随机效应合并优势比(OR)和95%置信区间(CI),以检查后期高残留牙齿数是否与痴呆风险降低相关。异质性由I 2测量。建议评估,开发和评估评级(GRADE)系统用于评估证据的整体质量。

文献检索最初包括419篇文章和11项研究(研究 入选年龄为52-75 岁,n = 28,894)最终被纳入分析。与低残留牙数组相比,高残留牙 数组痴呆风险降低约50%(汇总OR = 0.483; 95%CI 0.315至0.740; p  <0.001; I 2 = 92.421%)。然而,证据的总体质量被评为非常低。

尽管科学实力有限,但目前的荟萃分析报道残牙数量较高与晚年痴呆发生风险较低相关。

原始出处:

Oh B, Han DH, et al., Association between residual teeth number in later life and incidence of dementia: A systematicreview and meta-analysis. BMC Geriatr. 2018 Feb 17;18(1):48. doi: 10.1186/s12877-018-0729-z.

评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1974802, encodeId=fd4619e4802f0, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Thu Dec 06 06:13:00 CST 2018, time=2018-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826426, encodeId=397b18264260b, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Tue Dec 11 00:13:00 CST 2018, time=2018-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2021616, encodeId=90ce2021616d6, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Thu Mar 29 18:13:00 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-12-06 ms3025846204744509

    #BMC#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1974802, encodeId=fd4619e4802f0, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Thu Dec 06 06:13:00 CST 2018, time=2018-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826426, encodeId=397b18264260b, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Tue Dec 11 00:13:00 CST 2018, time=2018-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2021616, encodeId=90ce2021616d6, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Thu Mar 29 18:13:00 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-12-11 一叶知秋

    #发生率#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1974802, encodeId=fd4619e4802f0, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Thu Dec 06 06:13:00 CST 2018, time=2018-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826426, encodeId=397b18264260b, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Tue Dec 11 00:13:00 CST 2018, time=2018-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2021616, encodeId=90ce2021616d6, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Thu Mar 29 18:13:00 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-03-29 12498c32m68暂无昵称

    #GER#

    0