BMJ:医院患者高敏感性心肌钙蛋白I含量分布研究

2019-03-19 MedSci MedSci原创

研究发现,约有5%的医院患者其高敏感性心肌钙蛋白I超过临床界限,这一现象说明采用高敏感性心肌钙蛋白I浓度作为急性心肌梗死的诊断依据的局限性,临床中需要仔细分别以免误诊

近日研究人员就医院患者高敏感性心肌钙蛋白I(hs-cTnI)含量分布以及极高人群(超过99%的患者)的特征进行了考察。

20000名患者参与研究,研究的主要终点是所有参与者中hs-cTnI浓度分布,及极高人群的特异性。

研究发现,极高人群的hs-cTnI浓度为296 ng/L,而目前临床界限(ULN)为40 ng/L,约5%的参与者超过ULN(5.4%, n=1080)。在排除急性心肌梗死(n=122)和其他异常临床因素参与者(n=1707)后,极高人群的hs-cTnI浓度修正为189 ng/L,住院患者极高浓度为563 ng/L,门诊为65ng/L,急诊患者为215 ng/L。6.07% (n=225)的急诊患者、39.02%的ICU患者 (n=48)以及14.16%的住院患者(n=67)其hs-cTnI浓度超过ULN。

研究发现,约有5%的医院患者其高敏感性心肌钙蛋白I超过临床界限,这一现象说明采用高敏感性心肌钙蛋白I浓度作为急性心肌梗死诊断依据的局限性,临床中需要仔细分别以免误诊。

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    2020-05-24 chinapander2000

    学习了长知识了

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    学习了长知识了

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    学习了长知识了

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    学习了长知识了

    0

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    2020-05-20 chinapander2000

    学习了长知识了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=383090, encodeId=0e7938309088, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sun May 24 07:54:42 CST 2020, time=2020-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383064, encodeId=e99b383064e0, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sat May 23 06:28:02 CST 2020, time=2020-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383037, encodeId=eeee38303e06, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Fri May 22 05:56:30 CST 2020, time=2020-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383007, encodeId=75ac38300ef9, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Thu May 21 03:49:02 CST 2020, time=2020-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382982, encodeId=77ca3829820d, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Wed May 20 05:57:15 CST 2020, time=2020-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382953, encodeId=ade138295378, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Tue May 19 00:28:31 CST 2020, time=2020-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382928, encodeId=e4a938292803, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Mon May 18 05:29:33 CST 2020, time=2020-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382894, encodeId=f22638289438, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sun May 17 06:39:54 CST 2020, time=2020-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382866, encodeId=cf1c38286621, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sat May 16 04:42:07 CST 2020, time=2020-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382801, encodeId=5d9838280163, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Thu May 14 06:14:59 CST 2020, time=2020-05-14, status=1, ipAttribution=)]
    2020-05-19 chinapander2000

    学习了长知识了

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=383090, encodeId=0e7938309088, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sun May 24 07:54:42 CST 2020, time=2020-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383064, encodeId=e99b383064e0, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sat May 23 06:28:02 CST 2020, time=2020-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383037, encodeId=eeee38303e06, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Fri May 22 05:56:30 CST 2020, time=2020-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383007, encodeId=75ac38300ef9, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Thu May 21 03:49:02 CST 2020, time=2020-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382982, encodeId=77ca3829820d, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Wed May 20 05:57:15 CST 2020, time=2020-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382953, encodeId=ade138295378, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Tue May 19 00:28:31 CST 2020, time=2020-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382928, encodeId=e4a938292803, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Mon May 18 05:29:33 CST 2020, time=2020-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382894, encodeId=f22638289438, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sun May 17 06:39:54 CST 2020, time=2020-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382866, encodeId=cf1c38286621, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sat May 16 04:42:07 CST 2020, time=2020-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382801, encodeId=5d9838280163, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Thu May 14 06:14:59 CST 2020, time=2020-05-14, status=1, ipAttribution=)]
    2020-05-18 chinapander2000

    学习了长知识了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=383090, encodeId=0e7938309088, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sun May 24 07:54:42 CST 2020, time=2020-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383064, encodeId=e99b383064e0, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sat May 23 06:28:02 CST 2020, time=2020-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383037, encodeId=eeee38303e06, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Fri May 22 05:56:30 CST 2020, time=2020-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383007, encodeId=75ac38300ef9, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Thu May 21 03:49:02 CST 2020, time=2020-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382982, encodeId=77ca3829820d, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Wed May 20 05:57:15 CST 2020, time=2020-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382953, encodeId=ade138295378, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Tue May 19 00:28:31 CST 2020, time=2020-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382928, encodeId=e4a938292803, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Mon May 18 05:29:33 CST 2020, time=2020-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382894, encodeId=f22638289438, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sun May 17 06:39:54 CST 2020, time=2020-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382866, encodeId=cf1c38286621, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sat May 16 04:42:07 CST 2020, time=2020-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382801, encodeId=5d9838280163, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Thu May 14 06:14:59 CST 2020, time=2020-05-14, status=1, ipAttribution=)]
    2020-05-17 chinapander2000

    学习了长知识了

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=383090, encodeId=0e7938309088, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sun May 24 07:54:42 CST 2020, time=2020-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383064, encodeId=e99b383064e0, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sat May 23 06:28:02 CST 2020, time=2020-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383037, encodeId=eeee38303e06, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Fri May 22 05:56:30 CST 2020, time=2020-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=383007, encodeId=75ac38300ef9, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Thu May 21 03:49:02 CST 2020, time=2020-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382982, encodeId=77ca3829820d, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Wed May 20 05:57:15 CST 2020, time=2020-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382953, encodeId=ade138295378, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Tue May 19 00:28:31 CST 2020, time=2020-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382928, encodeId=e4a938292803, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Mon May 18 05:29:33 CST 2020, time=2020-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382894, encodeId=f22638289438, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sun May 17 06:39:54 CST 2020, time=2020-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382866, encodeId=cf1c38286621, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Sat May 16 04:42:07 CST 2020, time=2020-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382801, encodeId=5d9838280163, content=学习了长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe291299501, createdName=chinapander2000, createdTime=Thu May 14 06:14:59 CST 2020, time=2020-05-14, status=1, ipAttribution=)]
    2020-05-16 chinapander2000

    学习了长知识了

    0

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    2020-05-14 chinapander2000

    学习了长知识了

    0