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Pediatrics：乳酸杆菌治疗儿童腹泻

2015-01-14 MedSci MedSci原创译

乳酸杆菌腹泻呼吸道感染安慰剂双盲随机对照
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为了研究每日服用罗伊乳酸杆菌DSM 17938 对降低腹泻频次、持续时间和其他疾病结局的作用，来自墨西哥的研究者对当地4个日托中心对6-36个月儿童展开一项双盲的随机对照研究。总共纳入了所有护理中心的健康儿童，随机分组进行双盲、安慰剂对照研究。其中有168名儿童使用罗伊乳酸杆菌DSM 17938，168名儿童口服安慰剂，研究共持续了3个月，随后进行长达3个月的随访。结果发现，在3个月和6个月时，罗

为了研究每日服用罗伊乳酸杆菌DSM 17938 对降低腹泻频次、持续时间和其他疾病结局的作用，来自墨西哥的研究者对当地4个日托中心对6-36个月儿童展开一项双盲的随机对照研究。总共纳入了所有护理中心的健康儿童，随机分组进行双盲、安慰剂对照研究。其中有168名儿童使用罗伊乳酸杆菌DSM 17938，168名儿童口服安慰剂，研究共持续了3个月，随后进行长达3个月的随访。结果发现，在3个月和6个月时，罗伊乳酸杆菌DSM 17938显著降低了腹泻的频次、持续时间以及呼吸道感染性疾病的发生。另外，缺课次数、抗生素使用频率、患儿父母工作请假次数、就医次数等，结果都是实验组比安慰剂组要好。成本效益分析发现，罗伊乳酸杆菌治疗组比安慰剂组的成本低。两组实验都没有发现不良事件。研究结果表明，健康儿童每天去日托中心，服用罗伊乳酸杆菌DSM 17938能够显著降低腹泻的频次和持续时间以及呼吸道疾病的感染，并且为社区医疗降低了成本。原始出处： Gutierrez-Castrellon, P., et al., Diarrhea in preschool children and Lactobacillus re

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    2015-07-22 ms9608593228839890

    #DIA#

    0

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    2015-11-19 hbwxf

    #Pediatric#

    0

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    2015-04-16 feather89

    #PE#

    0

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    2015-01-16 陆成振

    #乳酸杆菌#

    0

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    2015-01-14 223.104.5.**

    吗咪爱有效的

    0