PCI术后应重视CIN

2012-06-17 范振光 临床心血管病杂志

       天津医科大学研究生院和天津市胸科医院心内科周小雨、李英、李珊珊等在《临床心血管病杂志》2012年第5期发表一项研究探讨了冠状动脉介入治疗(PCI)术后对比剂肾损伤(CIN)发病情况及危险因素。分析表明,CIN是PCI术后较常见的并发症,对具备CIN高危因素的患者,临床医生应高度重视。        

       天津医科大学研究生院和天津市胸科医院心内科周小雨、李英、李珊珊等在《临床心血管病杂志》2012年第5期发表一项研究探讨了冠状动脉介入治疗(PCI)术后对比剂肾损伤(CIN)发病情况及危险因素。分析表明,CIN是PCI术后较常见的并发症,对具备CIN高危因素的患者,临床医生应高度重视。
 
       研究者回顾性调查了天津市胸科医院心内科2009-01-2010-12行PCI术的1435例患者,根据是否发生CIN将其分为CIN组和非CIN组,比较2组之间相关因素的差异,应用Logistic回归分析确定CIN的危险因素。
 
       结果显示,1435例患者中有211例发生CIN,发病率为14.7%;CIN组和非CIN组间年龄、红细胞计数、血红蛋白含量、贫血、血压、左室射血分数(LVEF)、肾小球滤过率(GFR)、对比剂用量等均差异有统计学意义(均P<0.05)。多因素Logistic回归分析显示,年龄>70岁、糖尿病、低血压、贫血、LVEF≤45%、GFR≤60ml/(min.1.73m2)、对比剂用量>200ml、心肌梗死、急诊PCI是CIN的危险因素。

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    2012-10-09 kalseyzl
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    2012-11-02 zxl736
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