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Biofouling：耐热木聚糖酶可抑制和分解铜绿假单胞菌生物膜

2018-04-05 MedSci MedSci原创

木聚糖酶铜绿假单胞菌生物膜
关注

铜绿假单胞菌生物膜是亟待解决的问题，由于其耐药性而在慢性感染持续存在中起关键作用。在此研究中，研究人员探究了各种细胞壁降解酶抑制两种铜绿假单胞菌菌株PAO1和PA14的生物膜形成的能力。结果显示，木聚糖酶可明显抑制和分离铜绿假单胞菌生物膜而不影响浮游生长。木聚糖酶处理破坏细胞外聚合物质并降低铜绿假单胞菌菌株的粘度。然而，木聚糖酶处理不改变pyochelin，绿脓素，pyoverdine，假单胞菌喹

铜绿假单胞菌生物膜是亟待解决的问题，由于其耐药性而在慢性感染持续存在中起关键作用。在此研究中，研究人员探究了各种细胞壁降解酶抑制两种铜绿假单胞菌菌株PAO1和PA14的生物膜形成的能力。

结果显示，木聚糖酶可明显抑制和分离铜绿假单胞菌生物膜而不影响浮游生长。木聚糖酶处理破坏细胞外聚合物质并降低铜绿假单胞菌菌株的粘度。然而，木聚糖酶处理不改变pyochelin，绿脓素，pyoverdine，假单胞菌喹诺酮信号或鼠李糖脂的产生。另外，木聚糖酶的抗生物膜活性具有热稳定性，在45℃下可维持> 100天。

此外，木聚糖酶对一种耐甲氧西林金黄色葡萄球菌和两种大肠杆菌菌株具有抗生物膜活性。

原始出处：

Lee JH, Kim YG, Lee J. Thermostable xylanase inhibits and disassembles Pseudomonas aeruginosa biofilms. Biofouling. 2018 Apr 4:1-11. doi: 10.1080/08927014.2018.1440551.

评论区 (8)
#插入话题
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    2018-08-19 sunylz

    #Bio#

    0

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    2018-04-14 1e1c07bdm01(暂无匿称)

    好

    0

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    2018-04-08 txqjm

    谢谢了.学习

    0

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    2018-04-07 紫迎馨

    学习了

    0

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    2018-04-05 有备才能无患

    铜绿假单胞菌生物膜是亟待解决的问题.由于其耐药性而在慢**染持续存在中起关键作用.在此研究中.研究人员探究了各种细胞壁降解酶抑制两种铜绿假单胞菌菌株PAO1和PA14的生物膜形成的能力.

    0

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    2018-04-05 惠映实验室

    学习了.谢谢分享.

    0

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    2018-04-05 wqkm

    ^_^^_^^_^^_^

    0

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    2018-04-05 三生有幸9135

    学习一下谢谢分享

    0