BJU Int:低剂量率短距离放射治疗后局部复发前列腺癌的高强度聚焦超声抢救治疗分析

2019-06-13 AlexYang MedSci原创

最近,有研究人员评估了低剂量率短距离放射治疗后局部复发前列腺癌的高强度聚焦超声(S-HIFU)抢救治疗结果情况。研究包括了50名连续的患者,他们均为短距离放射治疗后局部复发前列腺癌患者并通过S-HIFU进行抢救治疗。研究发现,13名患者接受外照射治疗,37例接受近距离放射治疗,35例接受全腺治疗,15例接受半消融治疗。平均跟踪调查时间为4.6年。S-HIFU后,前列腺特异性抗原均值为0.3ng/m

最近,有研究人员评估了低剂量率短距离放射治疗后局部复发前列腺癌的高强度聚焦超声(S-HIFU)抢救治疗结果情况。

研究包括了50名连续的患者,他们均为短距离放射治疗后局部复发前列腺癌患者并通过S-HIFU进行抢救治疗。研究发现,13名患者接受外照射治疗,37例接受近距离放射治疗,35例接受全腺治疗,15例接受半消融治疗。平均跟踪调查时间为4.6年。S-HIFU后,前列腺特异性抗原均值为0.3ng/ml。在第6年,治疗失败无生存率、无进展生存率、总体生存率、肿瘤特异性生存率和无转移生存率分别为41%、45%、93%、98%和80%。近距离放射治疗与外照射后放射治疗相比,能够减少2-3级失禁情况(34% vs 62%, p=0.015)。与全腺治疗相比,失禁、膀胱出口梗阻和等级不小于III级的并发症在半消融治疗中显著减少(分别为14% vs 54%, p < 0.001; 13% vs 46%, p=0.03; 13% vs 63% p=0.001)。在S-HIFU之前,有25名患者的国际阴茎勃起功能指数不小于17,该值在治疗12个月时保留的比例为48%。

最后,研究人员指出,抢救性HIFU治疗有利于生存率,但是发病率高。专业的近距离放射治疗和半消融治疗能够提高治疗的安全性。

原始出处:


本文系梅斯医学(MedSci)原创编译整理,转载需授权!

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    2019-08-06 luoxiaog
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    2019-08-29 41514487@qq.com
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    2019-06-15 chg122

    #局部#

    0

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    2019-06-15 lfyang

    #抢救#

    0

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    2019-06-15 ms1292405679162969

    #低剂量#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1928284, encodeId=89441928284dc, content=<a href='/topic/show?id=c2b04e602af' target=_blank style='color:#2F92EE;'>#局部复发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47602, encryptionId=c2b04e602af, topicName=局部复发)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=02f5179, createdName=luoxiaog, createdTime=Tue Aug 06 17:11:00 CST 2019, time=2019-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2055076, encodeId=e8e420550e63f, content=<a href='/topic/show?id=6b148082247' target=_blank style='color:#2F92EE;'>#聚焦超声#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80822, encryptionId=6b148082247, topicName=聚焦超声)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Thu Aug 29 13:11:00 CST 2019, time=2019-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405914, encodeId=49ac14059147a, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Sat Jun 15 04:11:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1471368, encodeId=7a5614e1368de, content=<a href='/topic/show?id=ac13558e9cb' target=_blank style='color:#2F92EE;'>#抢救#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55879, encryptionId=ac13558e9cb, topicName=抢救)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be1a7117101, createdName=lfyang, createdTime=Sat Jun 15 04:11:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1480547, encodeId=d40e148054ea7, content=<a href='/topic/show?id=647d2615939' target=_blank style='color:#2F92EE;'>#低剂量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26159, encryptionId=647d2615939, topicName=低剂量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=97b17641126, createdName=ms1292405679162969, createdTime=Sat Jun 15 04:11:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604031, encodeId=6e3816040311f, content=<a href='/topic/show?id=67b81023e6ea' target=_blank style='color:#2F92EE;'>#高强度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102376, encryptionId=67b81023e6ea, topicName=高强度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79d219134728, createdName=aids219, createdTime=Sat Jun 15 04:11:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040476, encodeId=b19910404e699, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Thu Jun 13 16:11:00 CST 2019, time=2019-06-13, status=1, ipAttribution=)]
    2019-06-15 aids219

    #高强度#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1928284, encodeId=89441928284dc, content=<a href='/topic/show?id=c2b04e602af' target=_blank style='color:#2F92EE;'>#局部复发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47602, encryptionId=c2b04e602af, topicName=局部复发)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=02f5179, createdName=luoxiaog, createdTime=Tue Aug 06 17:11:00 CST 2019, time=2019-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2055076, encodeId=e8e420550e63f, content=<a href='/topic/show?id=6b148082247' target=_blank style='color:#2F92EE;'>#聚焦超声#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80822, encryptionId=6b148082247, topicName=聚焦超声)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Thu Aug 29 13:11:00 CST 2019, time=2019-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405914, encodeId=49ac14059147a, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Sat Jun 15 04:11:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1471368, encodeId=7a5614e1368de, content=<a href='/topic/show?id=ac13558e9cb' target=_blank style='color:#2F92EE;'>#抢救#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55879, encryptionId=ac13558e9cb, topicName=抢救)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be1a7117101, createdName=lfyang, createdTime=Sat Jun 15 04:11:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1480547, encodeId=d40e148054ea7, content=<a href='/topic/show?id=647d2615939' target=_blank style='color:#2F92EE;'>#低剂量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26159, encryptionId=647d2615939, topicName=低剂量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=97b17641126, createdName=ms1292405679162969, createdTime=Sat Jun 15 04:11:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604031, encodeId=6e3816040311f, content=<a href='/topic/show?id=67b81023e6ea' target=_blank style='color:#2F92EE;'>#高强度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102376, encryptionId=67b81023e6ea, topicName=高强度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79d219134728, createdName=aids219, createdTime=Sat Jun 15 04:11:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040476, encodeId=b19910404e699, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Thu Jun 13 16:11:00 CST 2019, time=2019-06-13, status=1, ipAttribution=)]
    2019-06-13 misszhang

    前列腺癌相关研究,学习了,谢谢梅斯

    0

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