Oncologist :肥胖类型对乳腺癌风险影响因HR状态而异

2017-09-24 佚名 肿瘤资讯

中国多中心研究:肥胖类型对乳腺癌风险的影响因HR状态而异。

中国多中心研究:肥胖类型对乳腺癌风险的影响因HR状态而异。


来自中国东北地区多中心大样本病例对照研究入组1439例年龄25-70岁确诊乳腺癌的汉族女性,对照组为门诊定期体检的健康人群,两组年龄、随访时间相仿。结果提示BMI、腰臀比与乳腺癌总风险成正比;BMI与ER+PR+乳腺癌风险、绝经前女性乳腺癌风险成正比;腰臀比与HR-乳腺癌风险成正比、与绝经前女性HR+乳腺癌风险成反比;腰臀比>0.85与绝经后女性HR-乳腺癌风险增加有相关。反映全身型肥胖的BMI与ER+PR+乳腺癌风险相关性更强,尤其绝经前女性;反映向心型肥胖的腰臀比,对HR-乳腺癌风险更有特异性,尤其绝经后女性。上述结果表明,不同类型肥胖可能对不同的乳腺癌亚型发挥不同的作用,对于不同肥胖类型女性,可能需要不同的化学预防策略。

原始出处:

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#插入话题
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    2018-03-25 sjq027

    #癌风险#

    0

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    2018-04-18 minlingfeng

    #Oncol#

    0

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    2018-07-05 gaoxiaoe
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    2017-09-26 july_977

    #GIST#

    0

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    2017-09-25 戒馋,懒,贪

    谢谢分享

    0

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    2017-09-24 明天会更好!

    谢谢分享.感觉收获很大!

    0

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