J Periodontal Res:吸烟习惯对种植体周围微生物群的调节作用

2018-11-21 MedSci MedSci原创

吸烟是种植体周围疾病的公认风险因素,并导致粘膜炎和种植体周围炎的微生物变化。然而,没有人知道吸烟对健康的种植体周围组织的影响。该研究的目的是评估具有健康种植体周围条件的吸烟者在种植体周围环境中的微生物组。

吸烟是种植体周围疾病的公认风险因素,并导致粘膜炎和种植体周围炎的微生物变化。然而,没有人知道吸烟对健康的种植体周围组织的影响。该研究的目的是评估具有健康种植体周围条件的吸烟者在种植体周围环境中的微生物组。

方法:在12名非吸烟(NSMK)和12名吸烟(SMK)的非牙周炎患者(无出血和探诊深度<4 mm)的单个临床健康,螺钉固位,牙齿包围的植入物周围收集种植体周围生物膜。分离细菌DNA,并使用焦磷酸测序对16S核糖体RNA基因文库进行测序,靶向V3-V4区域。使用Quantitative Insights into Microbial Ecology,Greengenes和Human Oral Microbiome Database数据库处理数据集。

结果:与NSMK微生物组相比,SMK种植体周围微生物组有明显差异,即使健康的种植体周围也有大量微生物种类。 SMK核心 微生物组有丰富的梭杆菌属,Tannerella和Mogibacterium,而NSMK核心 微生物组有大量的放线菌,Capnocytophaga和Streptococcus属。smk的微生物群间亲缘关系比nsmk的亲缘关系更近,说明不同的微生物群内聚力存在差异。

吸烟对种植体周围微生物群产生负面影响,导致疾病相关的状态,即使在临床健康的个体中也是如此。

原始出处:

Suzana P. Pimentel, et al.Smoking habit modulates peri‐implant microbiome: A case‐control study.Journal of Periodontal Research.2018 November. Doi:10.1111/jre.12597

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    2018-11-23 zhu_jun9837
  6. [GetPortalCommentsPageByObjectIdResponse(id=1702012, encodeId=a73b1e02012cf, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Mon Jan 14 14:04:00 CST 2019, time=2019-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1825001, encodeId=7c891825001d8, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Sat Jun 15 09:04:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727748, encodeId=49f41e27748bc, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Feb 24 11:04:00 CST 2019, time=2019-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343847, encodeId=c743134384ee3, content=<a href='/topic/show?id=d512e47853f' target=_blank style='color:#2F92EE;'>#种植体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74785, encryptionId=d512e47853f, topicName=种植体)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/TnzXXl41yf6V8fHrDb5JdtxOgpaY6vplUhHtL8BzDh1xMtcap9H1IOlE8umxPGovhIuVkeGTY26eNUFCFaOheQ/132, createdBy=29702500197, createdName=ms6279672939590805, createdTime=Fri Nov 23 13:04:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367767, encodeId=42ae136e7678b, content=<a href='/topic/show?id=2cee50e22c6' target=_blank style='color:#2F92EE;'>#微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50722, encryptionId=2cee50e22c6, topicName=微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Nov 23 13:04:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353385, encodeId=f5f235338504, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Nov 22 20:53:02 CST 2018, time=2018-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353290, encodeId=1467353290db, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Wed Nov 21 22:28:23 CST 2018, time=2018-11-21, status=1, ipAttribution=)]
    2018-11-22 医者仁心5538

    学习了

    0

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    2018-11-21 天地飞扬

    了解一下,谢谢分享!

    0

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